Exterior of Generac

Kathryn Hendee

Kathryn Hendee Kathryn Hendee 生物学 Assistant Professor 电子邮件: 凯瑟琳.hendee@veosonica.com 电话: 414.443.8606

Kathryn Hendee

教育

  • Postdoctoral Fellowship, Medical College of Wisconsin

  • Ph.D., Medical College of Wisconsin — Cell and Developmental 生物学

  • B.S., Wisconsin Lutheran College — 生物学

BACKGROUND

I became a member of the 生物学 faculty at WLC in 2022. In the interim between graduating from and returning to WLC, I ventured a few minutes north to the Medical College of Wisconsin; there I conducted graduate work studying rare pediatric genetic eye disorders and post-graduate work investigating how the formation of new blood vessels controls lung development, 老化, and regeneration. In my free time, I enjoy playing Ultimate Frisbee, singing in choir and playing my French horn at church, 园艺, 野营, 阅读, and watching science fiction and crime-solving shows.

教学

  • BIO 202 - Principles of 生物学 2
  • BIO 331 - Cell 生物学
  • BIO 355 - Pathophysiology
  • BIO 360 - Genetics
  • BIO 401 - ReSearch Strategies 1
  • BIO 402 - ReSearch Strategies 2
  • BIO 403 - ReSearch Strategies 3
  • LAS 401 - Liberal Arts Capstone

RESEARCH INTERESTS

My main interests are genetics, cell and molecular biology, and developmental biology. I am captivated by the intricate, 复杂的, beautiful design of the cell, especially our genetic makeup, and how such a tiny unit can perform so many functions and act in concert with trillions of other cells to form a living being. I am also intrigued by discerning disease processes and looking for potential therapeutic targets. I would like to generate animal or cell culture models of disease via genome editing technologies like CRISPR-Cas9 and then use the models to determine signaling mechanisms contributing to various disease phenotypes.

SCHOLARLY WORKS

  • Mammoto T., Hunyenyiwa T., P., Hendee K.马图斯,K.Rao, S.李,S. H.塔比马,D. M.纽约州切斯勒市. C., & Mammoto,. (2022). Hydrostatic pressure controls angiogenesis through endothelial YAP1 during lung regeneration. Frontiers in Bioengineering and Biotechnology, 10, 823642. PMID: 35252132.
  • Hunyenyiwa T., Hendee K.马图斯,K., P.猛犸象,T., & Mammoto,. (2021). Obesity inhibits angiogenesis through TWIST1-SLIT2 signaling. Frontiers in Cell and Developmental 生物学9, 693410. PMID: 34660572.
  • Hendee K., Hunyenyiwa T.马图斯,K.托莱多,M.A,猛犸象., & Mammoto T. (2021). Twist1 signaling in age-dependent decline in angiogenesis and lung regeneration. Aging (Albany NY), 13(6), 7781-7799. PMID: 33764901.
  • Mammoto,., Hendee K.M., & Mammoto T. (2020). Endothelial Twist1-PDGFB signaling mediates hypoxia-induced proliferation and migration of αSMA-positive cells. Scientific Reports, 10(1), 7563. PMID: 32371931.
  • Mammoto T.Torisawa, Y.S.M., Hendee K.Anugwom, C., Gutterman, D., & Mammoto,. (2019). Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1. Aging (Albany NY), 11(17), 7051-7069. PMID: 31487690.
  • Hendee K. E.索罗金纳,E. A.穆海森,S. S.里斯,我. M.泰勒,R. C.马尔科维奇,V.库图里洛,G.链接,B. A., & 精液,E. V. (2018). PITX2 deficiency and associated human disease: insights from the zebrafish model. Human Molecular Genetics, 27(10), 1675-1695. PMID: 29506241.
  • Hendee K. E.王,L. W.里斯,我. M.大米,G. M., Apte, S. S., & 精液,E. V. (2017). Identification and functional analysis of an ADAMTSL1 variant associated with a 复杂的 phenotype including congenital glaucoma, 颅面, and other systemic features in a three-generation human pedigree. Human Mutation, 38(11), 1485-1490. PMID: 28722276.
  • 里斯,我. M.泰勒,R. C.,嗯,E., Hendee K. E., Kariminejad, A., Abdul-Rahman, O.本·奥姆兰,T.曼宁,M。. A.叶斯利尤特,A.麦卡锡,C. A.kitner, T. E.科斯塔科斯,D., & 精液,E. V. (2016). 分析 CYP1B1 in pediatric and adult glaucoma and other ocular phenotypes. Molecular Vision22, 1229-1238. PMID: 27777502.
  • 里斯,我. M.泰勒,R. C.,嗯,E., Hendee K. E.席尔特,K. F.菲利普斯,J。. A.南卡罗来纳州塞奎拉市.A., & 精液,E. V. (2016). Whole exome sequencing identifies multiple diagnoses in congenital glaucoma with systemic anomalies. Clinical Genetics90(4), 378-382. PMID: 27272408.